FlowCam transparent particle images showing how thresholding works
The Benefits of Light and Dark Pixel Thresholding
Thresholding is a method of image segmentation used in image processing to discern the boundaries of an object from its background. Semi-transparent …
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Pre-filled syringe
What's the Value of Monitoring Silicone Oil Droplets in Protein Therapeutics?
Silicone oil droplets represent a particle type commonly present in protein-based biotherapeutics that are especially prevalent in products packaged …
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FlowCam collage of particles in a biotherapeutic sample
New Study from Osaka University Compares FlowCam, MFI, and iSpect Data
In order to gain the most comprehensive understanding of particles in their samples, researchers often employ several instruments as part of their …
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Rendering of FlowCam instruments for biopharma industry on lab table
Characterizing Protein Aggregation With Orthogonal and Complementary Analytical Techniques
A central challenge with particle analysis in biotherapeutics is the wide size range of particles that may be present, including particles from the …
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Stock photo of saline bag in hospital
FlowCam Demonstrates Degradation of Protein Formulations After Transport in IV Bags via Hospital Pneumatic Tube System
Subvisible particles in biotherapeutics represent critical quality attributes because they pose regulatory and potential product safety risks. …
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FlowCam Nano instrument rendering with submicron particles
White Paper: FlowCam Nano Provides Early Detection for Biotherapeutic Degradation and Contamination
Particles are ubiquitous in biotherapeutics and can drastically impact the efficacy of a given drug. Therefore, characterizing them is a critical …
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FlowCam collage of biopharma particles including protein aggregates, silicone oil, and contaminants
Characterization of Protein Aggregates and Other Particles in Biopharmaceuticals
Particulates are ubiquitous in parenteral drug products and remain a concern throughout their development and production. These particles must be …
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New Applications for FlowCam in Biotherapeutic Development
Many new types of biotherapeutic Active Pharmaceutical Ingredients (API) such as viruses, nanomedicines including virus-like particles and lipid …
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FlowCam collage of protein aggregates
Comparing FlowCam Results with Light Obscuration: A Study by Japan's National Institute of Health Sciences
In their recent publication, Quantitative Evaluation of Insoluble Particulate Matters in Therapeutic Protein Injections Using Light Obscuration and …
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VisualSpreadsheet Version 4 user interface showing particle collage and data
Morphological Filter Discrimination of Particulates in Injectable Therapeutic Formulations
Pharmaceutical and biopharmaceutical laboratories require rigid characterization of the particulate matter in injectable therapeutics. FlowCam …
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Pre-filled syringes
FlowCam Used to Study Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates
In a recent paper discussing particle counting and analytical techniques, the number and type of particles present in intravitreal injection …
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FlowCam collage of human cells
Flow Imaging Microscopy Guides Forced Degradation of Cell-based Medicinal Products
Cell-based medicinal products (CBMPs) offer promising opportunities for the treatment of diseases with previously limited or no therapeutic options. …
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