HTD Biosystems logo with a background of Bay Area scenery
Bay Area CDMO Offers FlowCam Analytical Services and Formulation Development
A conversation with HTD Biosystems HTD Biosystems provides services to accelerate the development of biotech drugs, liposomal drug delivery systems, …
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antibodies floating in space
Why is Protein Aggregate Analysis Important During Formulation Development?
The protein aggregate content in protein therapies and other biologic drug products is often a critical quality attribute that must be monitored. …
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scientist holding a drug vial
Developing Improved Protein-Like Particle Standards for Subvisible and Visible Particle Analysis
Protein aggregates in protein therapies can be difficult to monitor and measure in protein formulations due to their high transparency and irregular …
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Rendering of FlowCam instruments for biopharma industry on lab table
Characterizing Protein Aggregation With Orthogonal and Complementary Analytical Techniques
Strategies for monitoring particles in biopharmaceutical formulations are essential in the development and manufacturing of safe, effective drug …
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Pre-filled syringe
What's the Value of Monitoring Silicone Oil Droplets in Protein Therapeutics?
Silicone oil droplets are a common particle type found in protein-based biotherapeutics, often seen in products packaged as prefilled syringes. …
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Nurse with IV bag and patient in the background
Monitoring Subvisible Particle Formation in Infusion Bags Exposed to Stress Conditions
Agitation during transportation is one of the most ubiquitous stress conditions to which therapeutic protein formulations and other biotherapeutic …
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FlowCam images of IVIG proteins before and after drop shock
Study Uses FlowCam to Investigate Effects of Diluent and Silicone Oil on Particulate Formation in IV Bags
Protein aggregation is a major concern for biopharmaceuticals in post-production. Subvisible particles that form due to routine handling compromise …
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FlowCam collage of particles in a biotherapeutic sample
New Study from Osaka University Compares FlowCam, MFI, and iSpect Data
In order to gain the most comprehensive understanding of particles in their samples, researchers often employ several instruments as part of their …
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Stock photo of saline bag in hospital
FlowCam Demonstrates Degradation of Protein Formulations After Transport in IV Bags via Hospital Pneumatic Tube System
Subvisible particles in biotherapeutics represent critical quality attributes because they pose regulatory and potential product safety risks. …
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FlowCam collage of biopharma particles including protein aggregates, silicone oil, and contaminants
Characterization of Protein Aggregates and Other Particles in Biopharmaceuticals
Particulates are ubiquitous in parenteral drug products and remain a concern throughout their development and production. These particles must be …
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FlowCam collage of protein aggregates
Comparing FlowCam Results with Light Obscuration: A Study by Japan's National Institute of Health Sciences
In their recent publication, Quantitative Evaluation of Insoluble Particulate Matters in Therapeutic Protein Injections Using Light Obscuration and …
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Pre-filled syringes
FlowCam Used to Study Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates
In a recent paper discussing particle counting and analytical techniques, the number and type of particles present in intravitreal injection …
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