Stock photo of e. coli bacteria under microscope
Identifying Bacterial Contamination in FlowCam Samples
One of the main values of using flow imaging microscopy (FIM) when analyzing pharmaceuticals is the method's sensitivity to transparent particles. …
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Meeting USP Standards for Subvisible Particulate Matter with FlowCam LO
Assessing subvisible particle content is a required quality control step for biotherapeutics and other parenteral drug products. The United States …
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Scientist working in lab using pipettor
Optimizing Your FlowCam Context Settings: New Research Available
Optimizing FlowCam context settings and instrument parameters used during particle analysis is an important step in developing a protocol for …
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Woman scientist in lab using pipettor, with the word
Flow Imaging Microscopy for Subvisible Particle Analysis: A Webinar
Effective strategies for monitoring particles in biotherapeutics are critical to meet regulatory requirements like USP <788> and mitigate the …
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Nurse with IV bag and patient in the background
Monitoring Subvisible Particle Formation in Infusion Bags Exposed to Stress Conditions
Agitation during transportation is one of the most ubiquitous stress conditions to which therapeutic protein formulations and other biotherapeutic …
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Scientist pipetting sample into rack of vials
Analyzing Subvisible Particles in Protein and Cell & Gene Therapies
All types of biotherapeutics ranging from protein therapies to cell and gene therapies contain particles. While the types of particles can vary …
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AAPS eChalk Talks graphic
Orthogonal & Complementary Techniques: An Introductory Webinar
A central challenge with particle analysis in biotherapeutics is the wide size range of particles that may be present. Particles in these samples can …
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Webinar Series text over background of scientist pipetting in lab
USP Webinar Series: All the Particulars on Particles
Monitoring particles in biotherapeutics during manufacturing is critical to ensure product quality and to meet regulatory requirements on particle …
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Scientists in lab with test tubes, looking at data on monitor
What Does "Orthogonal Method" Mean for Particle Analysis?
Comprehensive characterization of biotherapeutics is often challenging given their complexity. In many cases, singular analytical methods cannot …
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FlowCam transparent particle images showing how thresholding works
The Benefits of Light and Dark Pixel Thresholding
Thresholding is a method of image segmentation used in image processing to discern the boundaries of an object from its background. Semi-transparent …
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Pre-filled syringe
What's the Value of Monitoring Silicone Oil Droplets in Protein Therapeutics?
Silicone oil droplets represent a particle type commonly present in protein-based biotherapeutics that are especially prevalent in products packaged …
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FlowCam collage of particles in a biotherapeutic sample
New Study from Osaka University Compares FlowCam, MFI, and iSpect Data
In order to gain the most comprehensive understanding of particles in their samples, researchers often employ several instruments as part of their …
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