Resources
Explore FlowCam technical content, ebooks, case studies, webinars, and videos. For applications including biopharma, water quality monitoring, aquatic research, and materials characterization.
Addressing Subvisible Silicone Oil Droplets
Industry Challenges, Analytical Strategies, and USP’s Rationale for a New General Informational Chapter
A webinar with USP and perspectives from Spheryx and FlowCam
March 4, 2026 | 10:00 AM – 12:00 PM EST
A webinar with USP and perspectives from Spheryx and FlowCam
March 4, 2026 | 10:00 AM – 12:00 PM EST
Introduction to Quantitative Plankton Imaging & EcoTaxa
Dr. Fabien Lombard, Laboratoire d'Océanographie de Villefranche (LOV)
Leah Anne Gibala-Smith, Yokogawa Fluid Imaging Technologies
March 17, 2026 | 10:00 AM – 11:00 PM EDT
Leah Anne Gibala-Smith, Yokogawa Fluid Imaging Technologies
March 17, 2026 | 10:00 AM – 11:00 PM EDT
Advancing Biologic and Parenteral Development Through Flow Imaging Microscopy
Positive Controls, Device Compatibility, and Investigational Case Studies
Speaker: Brooke Trimmer, Gilead Sciences
Speaker: Brooke Trimmer, Gilead Sciences
Enhancing Observational Capacity: FlowCam for Plankton Research & Monitoring
Learn how flow imaging microscopy increases sampling frequency, throughput, and data richness for plankton studies.
FlowCam for Harmful Algal Bloom Management in Drinking Water Utilities
Learn how FlowCam supports earlier detection and more targeted HAB response by directly imaging and quantifying the organisms driving bloom risk.
Capturing Secure, Traceable FlowCam Data with the Compliance Package for VisualSpreadsheet
Understand the requirements of 21 CFR Part 11 and how VisualSpreadsheet 6.1 supports FlowCam users in achieving compliance.
Optimizing Capture Settings on FlowCam 8000 Series Instruments
This technical note describes in detail how capture settings influence the ability for FlowCam to accurately size and count particles and provides a strategy for optimizing settings for specific applications.
Using VisualSpreadsheet to Create Metadata Tags and Export Data to EcoTaxa
VisualSpreadsheet 6.1 introduces powerful new features including customizable metadata tags and the ability to format data for EcoTaxa.
VisualSpreadsheet 6.1 Upgrade Guide
Download our guide to learn the differences between the software versions and decide if an upgrade is right for you.
Ensuring 21 CFR Part 11 Compliance with FlowCam
Learn how the Compliance Package for VisualSpreadsheet will empower you to achieve reliable, secure, and regulation-ready particle analysis.
Flow Imaging Microscopy in the Plankton Analysis Toolbox: Integrating FlowCam into Diverse Analytical Workflows
An introduction to FlowCam's operating principles and practical insight into its role within integrated aquatic workflows.
Optimizing Biologic Formulations Through Subvisible Particle Characterization
Insights from Flow Imaging Microscopy. A FlowCam webinar hosted by AAPS
Using FlowCam to Track Harmful Algal Bloom Dynamics in a Coastal Georgia Estuary
A webinar hosted by the Marine Technology Society and presented by researchers at Skidaway Institute of Oceanography.
Leveraging FlowCam for AI-Driven Plankton Classification
Key studies and best practices for data preparation and machine learning model validation using FlowCam images
Expanding Coastal Georgia HAB Research with FlowCam
This in-depth case study highlights how the Skidaway Institute of Oceanography uses FlowCam to monitor HAB-related risks to oyster larvae.
Spectroscopy: Analytically Speaking Podcast
Episode 37: On the Subject of Flow Imaging Microscopy in Collaboration with the American Association of Pharmaceutical Scientists.
High-Speed Imaging in Aquaculture: FlowCam Applications in Shellfish Hatcheries
This webinar begins with an overview of how FlowCam works, followed by examples of how hatcheries use FlowCam to quickly and reliably count, measure, and classify organisms in a standardized, high-throughput way.
Optimizing Biotherapeutic Formulations: The Role of Flow Imaging Microscopy
Learn how flow imaging microscopy works and relates to other particle characterization methods, and how FlowCam can support the development of safe, high-quality biotherapeutics.
An Exclusive Spectroscopy Interview on Flow Imaging Microscopy: Part 1
An interview with Dr. Austin Daniels in collaboration with the American Association of Pharmaceutical Scientists (AAPS)
An Exclusive Spectroscopy Interview on Flow Imaging Microscopy: Part 2
An interview with Dr. Austin Daniels in collaboration with the American Association of Pharmaceutical Scientists (AAPS)
Phytoplankton Identification Image Gallery
This plankton identification gallery provides example FlowCam images from freshwater, estuarine, and marine algal groups, including potential toxin producers, cyanobacteria, taste and odor producers, and shellfish HABs.
Quality Control of Organoid 3D Cell Clusters with FlowCam
Learn about the advantages of using FlowCam to asses iPSC culture optimization methods and a study performed in collaboration with Corning Life Sciences.
The Value of Plankton and Particle Imaging in Student-Led Research
Learn the importance of FlowCam to enhance student learning and research through examples from all academic levels.
Incorporating Advanced Microscopy Technology into STEM Education
A Case Study from the University of San Diego
Visible Particle Analysis in Biologics using Flow Imaging Microscopy
Learn how FlowCam can be used to detect visible and gray zone particles in protein therapy samples and gain insight into the types of particulates present.
Influential FlowCam Studies for Biopharmaceuticals
A digest of influential FlowCam studies in biopharmaceutical research.
Advancing Subvisible Particle Analysis
This ebook, produced in collaboration with AAPS, offers insights into the latest flow imaging microscopy applications for identifying subvisible particles, including relevant USP chapters.
Monitoring Subvisible Particles in Biotherapeutics
Flow Imaging Microscopy for Particle Quantification and Characterization
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Algae and Cyanobacteria Blooms - Track, Predict, and Identify
We partnered with AquaRealTime and Phytoxigene to present an example framework for a proactive and integrated monitoring program that guides you through the process of monitoring and identifying harmful algal blooms (HABs).
Using Flow Imaging Microscopy to Meet Particulate Matter Standards for Biotherapeutics
This webinar discusses how FIM instruments can help researchers align with USP guidance for monitoring subvisible particles and how this technique can be used to characterize visible particles to support visual inspection processes.
Using Trigger Mode with FlowCam 8400 Instruments
Sample preparation guidance to help FlowCam 8400 and FlowCam Cyano users quickly find the appropriate dilution factor required to achieve a target Particles per Used Image (PPUI) value of 1.20 or below.
USP Reference Standards for Subvisible Particulate Matter
A detailed review of the guidelines in USP <788>, <787>, and <789> and the recommendations in USP <1787> and <1788>.
Phytoplankton Monitoring in Gulf of Maine as a Signal of Climate Change Impacts
UNH research tracks the role of microscopic algae in sustaining marine biodiversity and ecosystems. Photo shared by University of New Hampshire.
Using File Processing Mode for FlowCam Method Development
A step-by-step guide to making the most of VisualSpreadsheet's File Processing Mode.
New Technology Helps Beat Back Harmful Algal Blooms
The Maryland Department of Natural Resources is identifying and controlling toxic algae several ways, from sophisticated imaging to sonic waves. Photo by AJ Metcalf/DNR.
Monitoring Microplastics Using Flow Imaging Microscopy
This application note describes advantages and limitations of traditional techniques for microplastics analysis and presents case studies that introduce Flow Imaging Microscopy as a high-throughput approach.
Monitoring Subvisible Particles in AAV Therapies with Flow Imaging Microscopy
This study shows how flow imaging microscopy can be used to monitor and minimize AAV aggregation and other subvisible particles found in gene therapies.
Flow Imaging Microscopy for Monitoring Particles in Gene Therapies
This webinar introduces FIM and discusses how it can be used to monitor subvisible particles in gene therapy drug products, including a case study in which FIM was used to analyze AAV formulations during an accelerated stability study.
Using FlowCam to Build Phytoplankton & HAB Community Composition Profiles Impacting Water Supplies
Speaker: Katherine McNaught, Passaic Valley Water Commission
Best Practices for Using FlowCam 8000 at Sea
Resources, suggestions, and best practices from scientists and technical experts to help you prepare your FlowCam for your next ocean research cruise and help you optimize your FlowCam time at sea.
Capture Settings for Biopharmaceutical Applications
Recommended capture settings and size parameters for accurately analyzing a variety of common particle types present in biopharmaceutical formulations
Monitoring Cleanliness in Electronics Manufacturing with Dynamic Image Analysis
An imaging-based analytical approach to particle monitoring, identification, and control in environments with strict cleanliness protocols.
FlowCam 8000 Series Brochure
FlowCam 8000 Series applications, technology, and specifications
FlowCam LO Brochure
FlowCam LO combines flow imaging microscopy and light obscuration
FlowCam Cyano Brochure
FlowCam Cyano applications and specifications
FlowCam 5000 Brochure
FlowCam 5000 applications and specifications
FlowCam Macro Brochure
FlowCam Macro applications and specifications
FlowCam Nano Brochure
FlowCam Nano applications and specifications
FlowCam 8000 and FlowCam VS Comparison
Side-by-side specification comparisons between FlowCam 8000 and FlowCam VS and a comparison of image quality
FlowCam University
Learning at your pace: virtual training courses for FlowCam 8000, FlowCam Cyano, FlowCam 5000, and VisualSpreadsheet
FlowCam Accessories
Order replacement parts, consumables, add-ons, and software
ALH for FlowCam Brochure
Benefits and specifications for ALH for FlowCam automated liquid handling
FlowCam Service Plans
Which plan is right for you?
FlowCam Applications: A - Z
A list of diverse samples analyzed in the FlowCam lab
Flow Imaging Microscopy for Subvisible Particle Analysis in Biotherapeutics
This webinar introduces flow imaging microscopy, an analytical technique commonly used to characterize subvisible particle content in biotherapeutic samples.
Salmon farm ‘FlowCam’ helping to monitor Clickimin Loch
A salmon farm company is offering its help to a local group concerned about the water quality at the Clickimin Loch in Lerwick.
VisualSpreadsheet Satellite Version
Analyze your FlowCam data on up to 3 external computers
Meeting USP Standards for Subvisible Particulate Matter with FlowCam
Flow Imaging Method
Flow Imaging Microscopy for Harmful Algal Bloom Monitoring
Feature article from Journal AWWA, April 2024 issue
Monitoring Subvisible Particles in Therapeutic Drug Products
AAPS News Magazine, March 2024
Bioscience Association of Maine Member Spotlight
Spotlight on Yokogawa Fluid Imaging Technologies
Flow Imaging Microscopy for Environmental and Agricultural Applications
Microplastics characterization, fiber analysis, atmospheric pollution, stormwater runoff contamination, livestock health, crop and soil sciences
An Overview of FlowCam for Aquatic Applications
The history and principles of FlowCam and case studies demonstrating how FlowCam is used for plankton research projects and algae monitoring programs
Meeting USP Standards for Subvisible Particulate Matter with FlowCam LO
Light Obscuration Method
Flow Imaging Microscopy for Shellfish Aquaculture and Research
A review of shellfish applications including: reproduction, larvae, microalgae cultivation, and predators
The Ultimate Guide to Flow Imaging Microscopy for Biotherapeutics
Flow Imaging Microscopy for biotherapeutic characterization, including protein formulations, and cell & gene therapies
The Ultimate Guide to Flow Imaging Microscopy for Aquatic Life Sciences
Flow Imaging Microscopy for the marine and freshwater applications including plankton research, aquaculture, water quality monitoring, and more
The Ultimate Guide to Flow Imaging Microscopy
Flow Imaging Microscopy is a powerful tool for detecting, identifying, and quantifying subvisible particles for a variety of applications
Detecting Contaminants in Stormwater Runoff with Hydro International
Customer: Hydro International
Monitoring for Taste & Odor Algae at Newport News Waterworks
How FlowCam is used by one drinking water utility
Protein Sciences Corporation Chooses FlowCam for Quality Analysis
Customer: Protein Sciences Corporation
FlowCam Biopharma Applications Brochure
An overview of FlowCam instruments and applications for biopharmaceuticals, including protein therapeutics and cell and gene therapy
FlowCam Materials Applications Brochure
An overview of FlowCam instruments and applications for materials characterization, including food and beverage, crop science, advanced materials, and more
Flow Imaging Microscopy Optimizes Processes in the Food Industry
Customer: CP Kelco
Ensuring the Quality of Hawaiian Microalgae
Customer: Cyanotech
FlowCam for Manufacturing and R&D Fluid Cleanliness Measurement
Customer: Hunting Energy Services
FlowCam Assists Harmful Algae Mitigation in Salmon Aquaculture
Read a case study featuring Scottish Sea Farms
Recent Notable FlowCam Studies in Aquatic Research
A digest of recently published studies in the fields of phytoplankton and zooplankton research.
Notable Studies Comparing FlowCam to Light Microscopy
A digest of influential FlowCam studies in comparing flow imaging microscopy to manual light microscopy.
What is Flow Imaging Microscopy?
Learn how Flow Imaging Microscopy works and see FlowCam in action
FlowCam Innovations for Biopharma
Learn about the variety of FlowCam solutions available for your biopharmaceutical application
FlowCam for Aquatic Research and Water Quality Monitoring
Learn how FlowCam can improve your water quality monitoring and marine and freshwater research.
Five Key Benefits of Automating Flow Imaging Microscopy
Introducing ALH for FlowCam automated liquid handling
Measuring Subvisible Particles and Aggregates using FlowCam LO
FlowCam LO combines flow imaging microscopy and light obscuration in a single instrument
Characterizing Protein Aggregation With Orthogonal and Complementary Analytical Techniques
A study showing how flow imaging microscopy and DLS can work together to provide a comprehensive picture of aggregation in your protein therapeutic
Robust AI Methods for Protein Biotherapeutics
VisualAI software for sample-agnostic image analysis with FlowCam
An Integrated and High-Speed Aproach to Monitoring Algae and Cyanobacteria
In Lakes, Reservoirs, and Finished Drinking Water
Notable FlowCam Studies on Cyanobacteria
A digest of influential FlowCam studies on cyanobacteria.
Early Detection of Aggregation in Formulations
FlowCam Nano for submicron particle characterization in biotherapeutics
Recommended Lab Equipment for FlowCam Users
A list of recommended items to help anyone setting up a new lab or who wants to ensure that all necessary items are available at installation.
FlowCam Aquatic Image Galleries
See what's possible with FlowCam
Orthogonal and Complementary Techniques: Combining FIM with LO to Characterize Biotherapeutics
Learn why it's important to characterize biotherapeutics with orthogonal techniques
FlowCam Macro Research Digest
FlowCam Macro publications demonstrate its value for zooplankton characterization in aquatic and environmental research
FlowCam Quantitative Metrics and Camera Settings
The effect of background intensity on particle image analysis
Using FlowCam Macro for the Study of Zooplankton
A conversation with Dr. Kathryn Cook
Flow Imaging Microscopy for Biopharmaceuticals
Four important considerations
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