The FlowCam 8000 Series is a high-throughput image-based particle analyzer with exceptional image quality and the widest size range available.
Analyze thousands of particles in less than a minute and comprehensively characterize the size, concentration, morphology, and identity of subvisible particles, cells, and microorganisms in their native solution.
FlowCam 8000 is an image-based particle size and shape analyzer that uses flow imaging microscopy to capture high-resolution images of particles in a fluid medium, combining the benefits of digital imaging, flow cytometry, and microscopy.
Image-based particle analysis allows for the comprehensive characterization of subvisible particles, API aggregates, and contaminants in biopharmaceuticals, as well as mammalian cells, microplankton, emulsions, and advanced materials.
FlowCam 8000 uses flow imaging microscopy to capture high-resolution images of particles, enabling users to analyze the shape, size, and count of subvisible particles and microorganisms.
| Specification | FlowCam 8100 | FlowCam 8400 | FlowCam Cyano |
| Applications | Biopharma, Aquatic, Materials | Aquatic | Aquatic |
| Size Range | 2 µm to 1 mm | 2 µm to 1 mm | 2 µm to 1 mm |
| Magnification | 20X, 10X, 4X, and 2X | 20X, 10X, 4X, and 2X | 20X, 10X, 4X, and 2X |
| Focus System | Automatic | Automatic | Automatic |
| Minimum Sample Volume | 100 µL | 100 µL | 100 µL |
| Flow Rate | 0.05 mL/min to 10 mL/min | 0.05 mL/min to 10 mL/min | 0.05 mL/min to 10 mL/min |
| High-Resolution Camera Type | Color or monochrome | Color | Color |
| Fluorescence excitation | None | 488 nm or 532 nm with 2-channel fluorescence detection | 633 nm with 2-channel fluorescence detection |
| Automated Liquid Handling Compatible? | Yes | Yes | Yes |
What is a particle analyzer?
Particle analyzers are analytical instruments used to examine small objects in a sample. Particle analysis instruments enable scientists to count and characterize particles in a wide range of sample types, including biopharmaceutical formulations, environmental samples, and advanced materials.
What is particle characterization, and why is it important?
Particle characterization refers to the strategies used to distinguish between particle and organism types based on size, shape, color, and other physical properties. This data can help researchers monitor and control unwanted and potentially harmful particle types. Instruments with high-resolution image quality provide reliable measurements of particle size and shape, enabling the distinction between particles with different characteristics.
Why is particle counting important?
The number of particles in a sample must be accurately enumerated to meet regulatory guidelines, ensure human and environmental safety, and quantify ecological changes over time. Instruments that offer accurate and repeatable concentration measurements help ensure that every decision is made with confidence.
What techniques are used for particle size and shape analysis?
Various techniques can be employed to characterize particles, depending on the specific information required and the desired level of automation. Some techniques include:
FlowCam 8000 uses Flow Imaging Microscopy to generate detailed visual and analytical data from particles in fluid samples.
How do I choose the right particle analysis instrument for my research?
The right particle analysis instrument should be able to monitor multiple relevant attributes of the contents of your samples. The size range of the instrument should also align with the sizes of the organisms and other objects you wish to characterize.
What is the value of imaging as it relates to particle size and shape analysis?
Images offer scientists a more comprehensive understanding of the appearance and structural characteristics of particles within a sample beyond the insights provided by basic size and shape measurements alone. Images are also a powerful visualization of the particle types in a sample when processing data, gaining insights, and communicating findings. High-quality particle images are necessary for identifying different plankton taxa, pharmaceutical contaminants, and other complex particle types in samples.
Tell us about your application and particle characterization needs.
We're happy to set up a call to discuss the proper FlowCam configuration for your application.
We'll follow up to discuss the quote and can set up a seminar, demonstration, or sample analysis.
